Trypanosomatid EST: a neglected information resource regarding flagellated protozoa?
نویسندگان
چکیده
منابع مشابه
Trypanosomatid EST: a neglected information resource regarding flagellated protozoa?
Expressed Sequence Tag (EST) sequence analysis rapidly gained widespread use and application for the discovery of gene transcripts in a variety of organisms (Adams et al. 1991). As of April 11, 2008, 51,391,051 ESTs entries were recorded in the dbEST NCBI (National Center of Biotechnology Information). Most of these (61%) are generated from laboratory models and economically important organisms...
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Flagellated protozoa that cause bronchopulmonary symptoms in humans are commonly neglected. These protozoal forms which were presumed to be "flagellated protozoa" have been previously identified in immunosuppressed patients in a number of studies, but have not been certainly classified so far. Since no human cases of bronchopulmonary flagellated protozoa were reported from Turkey, we aimed to i...
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A comparison of gene content and genome architecture of Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major, three related pathogens with different life cycles and disease pathology, revealed a conserved core proteome of about 6200 genes in large syntenic polycistronic gene clusters. Many species-specific genes, especially large surface antigen families, occur at nonsyntenic chromosome-...
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Trypanosomatid parasites containing a metabolically unstable ornithine decarboxylase (ODC) are naturally resistant to high levels of alpha-difluoromethylornithine (DFMO) because this ODC inhibitor, though causing a drastic reduction of intracellular putrescine, elicits only a moderate decrease of the spermidine endogenous pool. In this study we have used a combination of DFMO with cyclohexylami...
متن کاملCR-EST: a resource for crop ESTs
The crop expressed sequence tag database, CR-EST (http://pgrc.ipk-gatersleben.de/cr-est/), is a publicly available online resource providing access to sequence, classification, clustering and annotation data of crop EST projects. CR-EST currently holds more than 200,000 sequences derived from 41 cDNA libraries of four species: barley, wheat, pea and potato. The barley section comprises approxim...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2008
ISSN: 0074-0276
DOI: 10.1590/s0074-02762008000600021